site stats

Definition of lipophilic

WebLipophilicity synonyms, Lipophilicity pronunciation, Lipophilicity translation, English dictionary definition of Lipophilicity. adj. Soluble in fats or fat solvents. American Heritage® … Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such non-polar solvents are themselves lipophilic (translated as "fat-loving" or "fat-liking" ), and the axiom that "like dissolves like" generally holds true. Thus lipophilic substances tend to dissolve in other lipophilic substances, but hydrophilic ("water-loving") substances tend to dissolve in water and ot…

Lipophilicity - Wikipedia

WebOther articles where lipophilicity is discussed: surfactant: hydrophilic (water-soluble) and partly lipophilic (soluble in lipids, or oils). It concentrates at the interfaces between bodies or droplets of water and those of oil, or lipids, … WebOther articles where lipophilicity is discussed: surfactant: hydrophilic (water-soluble) and partly lipophilic (soluble in lipids, or oils). It concentrates at the interfaces between bodies or droplets of water and … sigil of lilith ring https://nhukltd.com

Drug Lipophilicity and Absorption: The Continuous …

WebLipophilicity is an important physicochemical parameter to link membrane permeability and, drug absorption and distribution with the route of clearance (metabolic or renal). Measuring the compound lipophilicity is readily amenable to automation. WebNov 8, 2024 · Lipophilicity is a measure for the tendency of a compound to partition into nonpolar (organic) solvent (versus aqueous solvent). Most small molecules/ions need the assistance of specific protein channels to transport them through the cell membrane. These inside-out protein channels are called transporters. Webhaving an affinity for lipids. Test prep from the experts. Boost your test score with programs developed by Vocabulary.com’s experts. sigil of jophiel

Lipophilicity Descriptors: Understanding When to Use LogP

Category:Definition of lipophilic - Chemistry Dictionary

Tags:Definition of lipophilic

Definition of lipophilic

What does lipophilic mean? - Definitions.net

WebMay 24, 2024 · lipophilic: [adjective] having an affinity for lipids (such as fats). Webdefinition measure of... P; balance between lipophilicity and hydrophilicity of a compound in the un-ionized form; measure of the relative affinity of the compound for lipids (specifically, n-octanol) as compared to water To determine the partition coefficient, one would dissolve the compound in question in a container with n-octanol and water.

Definition of lipophilic

Did you know?

WebThe ionization state of a molecule can impact its lipophilicity. This leads to the definition of the distribution coefficient (logD) of a compound, which takes into account the … Web1 day ago · It is occasionally used as a solvent, being weakly polar and lipophilic, but its close relative ethyl acetate is a more common solvent being less toxic and less soluble in water.

WebThe use of PTHF, commercially available in a variety of molecular weights, enables better tuning of the length of the hydrophobic fragment in macromolecules, while the presence of PEG chains allows direct comparison of AIPEs-1 and AIPEs-2 in terms of the effect of macromolecular composition on micellization and other colloidal properties. WebMar 6, 2024 · Cholesterol is a lipophilic molecule that is essential for human life. It has many roles that contribute to normally functioning cells. For example, cholesterol is an important component of the cell …

WebLipophilic efficiency [1] ( LiPE ), sometimes referred to as ligand-lipophilicity efficiency ( LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness. [2] [3] For a given compound LiPE is defined as the pIC 50 (or pEC 50 ...

WebMeaning of lipophilic. What does lipophilic mean? Information and translations of lipophilic in the most comprehensive dictionary definitions resource on the web.

WebLipophilic definition, having a strong affinity for lipids. See more. the prince of cryptoWebLipophilic definition: having an affinity for lipids Meaning, pronunciation, translations and examples sigil of lucifer white transparent backgroundWebAug 7, 2012 · Since lipophilicity is a key determinant in BBB permeability, lipidization, that is, conversion of the drug moiety into a more lipophilic form by the insertion of … the prince of cumberland quoteWebDefinition: Lipophilic or 'lipid-loving' molecules are attracted to lipids. A substance is lipophilic if it is able to dissolve much more easily in lipid (a class of oily organic compounds) than in water. Source: GreenFacts More: The degree of lipophilicity is expressed as octanol-water partitioning coefficient: Kow. Source: GreenFacts sigil of lilith pendantWeblipophilic definition: 1. Lipophilic substances are attracted to lipids (= fats, oils, or waxes that dissolve in alcohol…. Learn more. sigil of malice gw2WebDefinition of lipophilic Literally "fat-loving". Applied to molecular entities (or parts of molecular entities) having a tendency to dissolve in fat-like (e.g. hydrocarbon) solvents. See also hydrophilic , hydrophobic interaction. Search the Dictionary for More Terms the prince of cumberlandWebThe drug is highly lipophilic and able to cross the blood brain barrier at higher doses. From Wikipedia Sulbutiamine overcomes the poor oral bioavailability of thiamine because it is … sigil of lucifer wallpaper