Systemic sclerosis (SSc) is an autoimmune inflammatory condition. It results in potentially widespread fibrosis and vascular abnormalities, which can affect the skin, lungs, gastrointestinal tract, heart and kidneys. The skin becomes thickened and hard (sclerotic). Systemic sclerosis has been subdivided into two main … See more Systemic sclerosis is rare, with prevalencevarying from 30–500 cases per million. 1. It is up to 5 times more common in females compared to males. 2. All races and ethnicities may be affected, but rates appear to be slightly … See more Systemic sclerosis is an autoimmune condition characterised by inflammation, fibrosis and vasculopathy. The precise underlying … See more The clinical features of systemic sclerosis are related to underlying vascular, inflammatory and fibrotic disease. Constitutional symptoms are common, such as fatigue, … See more Web4 Apr 2024 · The National Scleroderma Foundation Support Community connects patients, families, friends and caregivers for support and inspiration. This community is sponsored by the National Scleroderma Foundation, an Inspire trusted partner.
Scleroderma - Symptoms and causes - Mayo Clinic
Web23 Dec 2024 · CREST syndrome is a type of scleroderma that affects the skin, small blood vessels, joints, lungs, and other organs. It can cause symptoms such as Raynaud’s phenomenon, swelling and stiffness... WebIntroduction. Systemic sclerosis sine scleroderma (ssSSc) is characterized by internal organ involvement and serologic abnormalities in the absence of cutaneous manifestations of systemic sclerosis. 1 Systemic sclerosis or scleroderma disorders comprise a heterogeneous group of conditions of unknown etiology and is characterized by the … buffet in cherry hill
CREST Syndrome: Background, Pathophysiology, Etiology
Web29 Jul 2024 · Pulmonary manifestations of scleroderma are demonstrated histologically in 90% of patients with scleroderma. It is a leading cause of mortality and at autopsy the lung is reportedly involved in close to 100% of cases. However, only 25% of patients will present with respiratory symptoms or demonstrate abnormalities on CT 4 . Web5 Oct 2024 · CREST ( calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome is a member of the heterogeneous group of … WebWhat is CREST syndrome? Scleroderma is a rare autoimmune connective tissue disorder. It is recognized by abnormal thickening of the skin. 1 CREST syndrome is a type of scleroderma called limited scleroderma. 2 CREST is an acronym for symptoms of the disease. 1,2 C stands for calcinosis. buffet in chesterfield mo